Telmisartan 40mg

Empress T

Technically Empress T is a Blend of N-Methylglucamine with specific pH stabilizers as in case of Telmisartan we need to increase the pH to enhance the absorption of API in given media , so Empress T helps the drug to release in that level

Physical properties of tablets

Procedure

• • Slurry preparation:
    1. Dissolve Empress T in about same volume of IPA , now slowly add Telmisartan and aerosil 200 and stir it continuous to prepare slurry and keep it aside for 4 hours ( minimum recommended)
  • Binding and sizing:
    1. Now add, Mannitol, Lactose in the above written step and stir it and mix well to for wet mass
    2. Dry the wet mass the temperature of FBD or tray drier Strictly to be kept BELOW 40Oc as the drying of temperature will degrade the drug
    3. Pass the semidry mass through # 10 sieve or 8mm Perforated screen.
    4. Dry the granules till LOD remains below 2 %.
    5. Again pass through 24 # mesh.
  • Lubrication:
    1. Sift the Magnesium Stearate, Cross Povidone, CCS, and Talc through 60# sieve separately, and Aerosil through 40# sieve.
    2. Mix above mixture in suitable blender.
    3. Compress the tablet having hardness 5-6 kg/cm2.

Note :

1. This is the tentative formulation and the information is based on laboratory work with small scale equipment and does not indicate the product performance.
2. Full scale testing and end product performance are the responsibility of the user.
3. We suggest that you may be increase or decrease the quantity of polymer and types of Excipients according to your final formulation/requirements.